Description

Name: alpha-MSH(11-13); KPV; Lys-Pro-Val
CAS No.: 67727-97-3
Peptide Sequence: H-Lys-Pro-Val-OH
Molecular Formula: C16H30N4O4
Molecular Weight: 342.43
Appearance: White Lyophilized powder

KPV (ACTH(11-13), alpha-MSH)

KPV is the C-terminal peptide fragment of alpha-melanocyte stimulating hormone (alpha-MSH). It is one of many short peptide derivatives of alpha-MSH that has been tested to determine if they retain similar photoprotective properties, activity against ischemia, sexual effects, or benefits on feeding behavior and energy homeostasis. KPV, which is made up of lysine-proline-valine turns out to have significant anti-inflammatory effects[1]. The peptide is under active research as a potential therapeutic in the treatment of inflammatory bowel disease. It has shown evidence of potent anti-inflammatory activity in the central nervous system, GI tract, lungs, vascular system, and joints. Because KPV is a small peptide, it can be administered in multiple ways including oral, intravenous, and transdermal routes.